Aminomethyl Resin
Although this resin is not used directly in peptide synthesis, it is the core of a
wide variety of synthesis resins. Coupling linker compounds to aminomethyl
resin through an amide bond is a convenient method of preparing stable resins
with many unique properties.
Aminomethyl resin potentially has more direct use in solid phase organic
synthesis. It could be used to anchor aldehydes by forming an imine group and
could be useful in the synthesis of amines. It has also been used in solution
phase chemistry as a scavenger for the easy removal of excess electrophiles in
the presence of non-electrophiles.
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