欢迎光临~西安蓝晶生物科技有限公司
语言选择: 中文版 ∷  英文版

多肽合成树脂

  • 2-chlorotrityl chloride resin
2-chlorotrityl chloride resin

2-chlorotrityl chloride resin

  • 交联度:1%-2%DVB
  • 粒径:100-200目
  • 取代度:0.3-1.6mmol/g
  • Appearance:off-white to yellow beads
  • 产品描述:
  • 在线订购
2-Chlorotrityl Chloride resin is a slightly less acid-labile than Trityl resin and thus more widely used in solid phase peptide synthesis . This resin has been also widely used in solid phase organic synthesis by immobilizing carboxylic acid , alcohols , phenols , amines , imidazoles, hydroxylamines , and thiols  on it. Cleavage is achieved using AcOH/TFE/DCM [1-6], 0.5% TFA or HFIP in DCM, or 1-5% TFA in DCM containing 5% TIS. Trityl linkers have certain advantages in comparison to the alkoxybenzyl alcohol (eg. Wang resin), especially in the area of peptide chemistry. First, the problem of recemization during the loading of the first amino acid (using DIPEA) is avoided with trityl linkers. Second, due to steric factors, no diketopiperazine formation is observed .
上一个:王树脂 下一个:Aminomethyl resin
用手机扫描二维码关闭
二维码